About the Department

The Department of Molecular Biology & Biotechnology (MBBT) of Cotton University had its genesis as the Department of Biotechnology in the erstwhile Cotton College in 2008, offering an undergraduate, BSc in Biotechnology (Hons) programme. Subsequently, the postgraduate programme of M.Sc in Molecular Biology & Biotechnology (MBBT) was initiated in 2015. With Cotton University Act 2017, coming into force, the departments of Biotechnology and MBBT were unified as the Department of Molecular Biology & Biotechnology (MBBT) on January 1, 2018. The department currently has six permanent faculty, one scientific assistant and a few contractual staff. Currently, the department offers undergraduate, post-graduate and PhD programmes. The areas of research...

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Head of the Department

Recent Publications

  • Pinky Bora · Nameirakpam Nirjanta Devi, Bioremediation of Heavy Metal Lead (Pb) by Enteric Bacteria and Metagenomic Analysis of an Endogenic Earthworm Metaphire nanaoensis Found in the Semi‐urban Paddy Fields of Kamrup District, Assam, Water Air Soil Pollution , 367, [2024], https://doi.org/10.1007/s11270-024-07170-w

  • Meghna Santoshi · Bharat Engleng · Sachin M. Eligar · Immadi Siva Ratnakar · Easa Nagamalleshwari · Valakunja Nagaraja, Identification and characterization of a new HNH restriction endonuclease with unusual properties, Applied Microbiology and Biotechnology , [2023], https://doi.org/10.1007/s00253-023-12717-8

  • Pinky Bora and Nameirakpam Nirjanta Devi, Exploration of the chemical constituents and its antioxidant, antibacterial activities of endophytic fungi isolated from the medicinal plant Dillenia indica, Archieves of Microbiology , [2023]

  • Kashyap N, Islam M, Kaur H, Tiwari D, Begum A, Bose M, Das CR, Saikia AK, Kalita P, Bose PD, Bose S, Oxidative stress-A key determinant of complications and negative outcome in hepatitis E virus infected pregnancies, Journal of Medical Virology , [2023], 10.1002/jmv.28576

  • Chayanika Chaliha, Richa Srivastava, Eeshan Kalita*, Lingaraj Sahoo, Praveen Kumar Verma, Rapid and precise detection of cryptic tea pathogen Exobasidium vexans: RealAmp validation of LAMP approach, World Journal of Microbiology and Biotechnology , vol.39, 52, [2023], https://doi.org/10.1007/s11274-022-03506-y

  • Julie Baruah, Pritam Bardhan, Ashis K Mukherjee, Ramesh Chandra Deka, Manabendra Mandal, Eeshan Kalita*, Integrated pretreatment of banana agrowastes: Structural characterization and enhancement of enzymatic hydrolysis of cellulose obtained from banana peduncle, International Journal of Biological Macromolecules , vol.201, 298-307, [2022], https://doi.org/10.1016/j.ijbiomac.2021.12.179

  • C Chaliha, J Baruah, E. Kalita*, Nanoarchitectonics of crosslinked Cu:ZnS-lignocellulose nanocomposite: a potent antifungal and antisporulant system against the tea pathogen Exobasidium vexans., JIOPM-Journal of Inorganic and Organometallic Polymers and Materials , vol.32, , 954–966, [2022], https://doi.org/10.1007/s10904-022-02225-z

  • Shantanu Aggarwal, Sayan Mondal, Soumik Siddhanta, Bharat Engleng , Easa Nagamalleswari, Valakunja Nagaraja,* and Chandrabhas Narayana*, Divalent Ion-Induced Switch in DNA Cleavage of KpnI Endonuclease Probed through Surface-Enhanced Raman Spectroscopy, The Journal of Physical Chemistry B , [2021], https://dx.doi.org/10.1021/acs.jpcb.0c10667

  • Begum A, Mishra A, Das CR, Das S, Dutta R, Kashyap N, Bose PD, Bose S, Impact of TNF-α profile in recurrent pregnancy loss pathogenesis: A patient based study from Assam, J Reprod Immunol , [2021], 10.1016/j.jri.2021.103430

  • Tiwari D, Das CR, Sultana R, Kashyap N, Islam M, Bose PD, Saikia AK, Bose S, Increased homocysteine mediated oxidative stress as key determinant of hepatitis E virus (HEV) infected pregnancy complication and outcome: A study from Northeast India, Infection Genetics and Evolution , [2021], 10.1016/j.meegid.2021.104882

  • Raju Bharalee, Genetic Diversity and Population Structure of a Medicinal Herb Houttuynia cordata Thunb. of North-East India, Plant Mol Biol Report , vol.39, 434–442, [2021], 10.1007/s11105-020-01260-9

  • Lambert Academic Publishing, Book Title: Deciphering Transcriptome Derived Drought Tolerance Mechanism in Tea-Exploring Candidate Genes for Enhance Drought Tolerance. Lambert Academic Publishing, Germany,  ISBN No. 978-620-2-5232, Book , [2020]

  • Khan, Mohammad & Tiwari, Diptika & Dongre, Anita & Rehman, Sadaf & Mustafa, Saad & Das, Chandana & Massey, Sheersh & Bose, Purabi & Bose, Sujoy & Husain, Syed, Exploring the p53 connection of cervical cancer pathogenesis involving north-east Indian patients, PLoS ONE , [2020], 10.1371/journal.pone.0238500

  • Tiwari D, Ray Das C, Sultana R, Kakoti S, Aasif Khan M, Dongre A, Husain SA, Bose PD, Bose S , Impact of modulation of telomerase and cancer stem-cell marker OCT4 axis in cervical cancer pathogenesis with underlying HPV16 infection, J Cell Biochem , [2020], 10.1002/jcb.29501

  • Dibyayan Deb, Santanu Das, Atanu Adak, Mojibur R Khan , Traditional rice beer depletes butyric acid-producing gut bacteria Faecalibacterium and Roseburia along with fecal butyrate levels in the ethnic groups of Northeast India, 3 Biotech (2020) 10:283 Springer , [2020], https://10.1007/s13205-020-02280-8

  • Suruchi Aggarwal, Ajay Kumar, Shilpa Jamwal, Mukul Kumar Midha, Narayan Chandra Talukdar, and Amit Kumar Yadav, HyperQuant-A Computational Pipeline for Higher Order Multiplexed Quantitative Proteomics , ACS Omega , vol.5, 10857–10867, [2020], https://10.1021/acsomega.0c00515

  • Suruchi Aggarwal, Sanjay K. Banerjee, Narayan Chandra Talukdar,and Amit Kumar Yadav, Post-translational Modification Crosstalk and Hotspots in Sirtuin Interactors Implicated in Cardiovascular Diseases, Frontiers Media S.A. Front. Genet , [2020], https://doi.org/10.3389/fgene.2020.00356

  • Springer, Genetic Diversity and Population Structure of a Medicinal Herb Houttuynia cordata Thunb. of North-East India., Plant Molecular Biology Reporter (2020); https://doi.org/10.1007/s11105-020-01260-9 , [2020]

  • Bharat Engleng, Manika D Kataki, From Cellular Defenses to Workhorses of Molecular Biology, The Chemical Axis , vol.Volume 19, No. 1, [2019]

  • Medscape, Impact of modulation of telomerase and cancer stem-cell marker OCT4 axis in cervical cancer pathogenesis with underlying HPV16 infection., Journal of cellular biochemistry; 2020 Apr;121(4):2782-2791. , [2019]

  • BABRONE, College of Veterinary Science, Assam Agricultural University, Khanapara, Recent Advances in Cancer Immunotherapy, BioNE, E-zine of Biological Sciences. ISSN: 2456-7264 | Issue – 12 | , [2019]

  • Tiwari D, Ray Das C, Sultana R, Kakoti S, Aasif Khan M, Dongre A, Husain SA, Bose PD, Bose S, Impact of modulation of telomerase and cancer stem-cell marker OCT4 axis in cervical cancer pathogenesis with underlying HPV16 infection, J Cell Biochem , [2019], 10.1002/jcb.29501

  • Springer, Transgenic Tea Over-expressing Solanum tuberosum Endo-1,3-beta-D-glucanase Gene Conferred Resistance Against Blister Blight Disease, Plant Molecular Biology Reporter(2018) 36:107–122 , [2018]

  • Das CR,Tiwari D,Dongre A, Khan MA, Husain SA, Sarma A,Bose S,Bose PD, Deregulated TNF-Alpha Levels Along with HPV Genotype 16 Infection Are Associated with Patients, , [2018], 10.1089/vim.2017.0151

  • Tiwari D, Das CR, Bose PD, Bose S, Associative role of TYMS6bpdel polymorphism and resulting hyperhomocysteinemia in the pathogenesis of preterm delivery and associated complications: A study from Northeast India, Gene , [2017], 10.1016/j.gene.2017.06.023

  • Tiwari D, Bose PD, Sultana R, Das CR, Bose S, Preterm delivery and associated negative pregnancy outcome - A tale of faulty progesterone receptor signaling pathway and linked derailed immunomodulation: A study from Northeast India, J Reprod Immunol , [2016], 10.1016/j.jri.2016.10.001

  • Tiwari D, Bose PD, Das S, Das CR, Datta R, Bose S, MTHFR (C677T) polymorphism and PR (PROGINS) mutation as genetic factors for preterm delivery, fetal death and low birth weight: A Northeast Indian population based study, Meta Gene , [2015], 10.1016/j.mgene.2014.12.002

  • Das CR, Deka M, Bose S, Bose PD, Das GC, Demographic profile of Cervical Cancer develop-pment: a hospital based study, International Journal of Medical Research and Review , [2014]

  • Bose PD, Das BC, Hazam RK, Kumar A, Medhi S, Kar P, Evidence of extrahepatic replication of hepatitis E virus in human placenta, J Gen Virol , [2014], 10.1099/vir.0.063602-0

  • Goel V, Bose PD, Sarma MP, Hazam RK, Das BC, Gondal R, Kar P, Chemokine receptor 5 (CCR5) polymorphism in chronic hepatitis B patients treated with three different nucleos(t)ide analogues, Indian J Med Res , [2013]

  • Medhi S, Deka M, Deka P, Swargiary SS, Hazam RK, Sharma MP, Gumma PK, Asim M,Kar P, Promoter region polymorphism & expression profile of toll like receptor-3 (TLR-3) gene in chronic hepatitis C virus (HCV) patients from India, Indian J Med Res , [2011]

  • Bose PD, Das BC, Kumar A, Gondal R, Kumar D, Kar P, High viral load and deregulation of the progesterone receptor signaling pathway: association with hepatitis E-related poor pregnancy outcome., Journal of Hepatology , [2011], 10.1016/j.jhep.2010.08.037

  • Bose PD, Sarma MP, Medhi S, Das BC, Husain SA, Kar P, Role of polymorphic N-acetyl transferase2 and cytochrome P4502E1 gene in antituberculosis treatment-induced hepatitis, J Gastroenterol Hepatol , [2011], DOI: 10.1111/j.1440-1746.2010.06355.x

  • Deka M, Bose M, Baruah B, Bose PD, Medhi S, Bose S, Saikia A, Kar P, Role of CYP2E1 gene polymorphisms association with hepatitis risk in Northeast India, World J Gastroenterol , [2010], DOI: 10.3748/wjg.v16.i38.4800

  • Medhi S, Potukuchi SK, Polipalli SK, Swargiary SS, Deka P, Chaudhary A, Begum N, Hussain Z, Ahlawat RS, Kar P, Diagnostic utility of hepatitis C virus core antigen in hemodialysis patients, , [2008], doi: 10.1016/j.clinbiochem.2007.12.024

  • Purabi Deka and MC Kalita , In vitro clonal propagation and oragnogenesis in Spilanthes acmella (L) Murray. A herbal pesticidal plant of Northeast India, Plant Biochemistry and Biotechnology , [2005], https://doi.org/10.1007/BF03263230

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Scholarly Resources

  • Publications 36
  • Conference/In Proceedings
  • Book/Book Chapter